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Inflammation (2013) 36(4):88896

The double-blind multicenter phase 3 trials STEP 1, 3, 4, 5 were conducted in adults (mean age 46.247.3 years), mostly females, with obesity or overweight with 1 weight-related complication (mean BMI 37.838.4 kg/m 2 ) and aimed to demonstrate the superiority of semaglutide 2.4 mg over placebo in BW lowering at 68 or 104 24 weeks as an adjunct to diet and physical activity 23

CagrilintideSemaglutide in Adults with Overweight or Obesity and Type 2 Diabetes (REDEFINE 2)

It is most commonly stacked with NAD+ or Semax because they target complementary biological layers rather than overlapping ones